Description
Product Characteristics:
Aliases: C8A antibody, CO8A_HUMAN antibody, Complement component 8 subunit alpha antibody, Complement component 8, alpha polypeptide antibody, Complement component C8 alpha chain antibody
Target Information: C8 is a component of the complement system and contains three polypeptides, alpha, beta and gamma. This gene encodes the alpha subunit of C8. C8 participates in the formation of the membrane attack complex (MAC). The MAC assembles on bacterial membranes to form a pore, permitting disruption of bacterial membrane organization. Mutations in this gene cause complement C8 alpha-gamma deficiency. [provided by RefSeq, Nov 2008]